D-Valine
SIGMA/V1255 - BioReagent, suitable for cell culture
Synonym: (R)-α-Aminoisovaleric acid; D-
CAS Number: 640-68-6
Empirical Formula (Hill Notation): C5H11NO2
Molecular Weight: 117.15
EC Number: 211-368-9
MDL Number: MFCD00064219
Linear Formula: (CH3)2CHCH(NH2)CO2H
Product Type: Chemical
biological source | synthetic (organic) |
form | powder |
InChI | 1S/C5H11NO2/c1-3(2)4(6)5( |
InChI key | KZSNJWFQEVHDMF-SCSAIBSYSA |
mp | >295 °C (subl.) (lit.) |
product line | BioReagent |
Quality Level | 200 |
shipped in | ambient |
SMILES string | CC(C)[C@@H](N)C(O)=O |
storage temp. | room temp |
technique(s) | cell culture | mammalian: suitable |
Application: | • Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture • endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture • DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture |
Biochem/physiol Actions: | |
Biochem/physiol Actions: | D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells. |
General description: | L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine. |
Packaging: | 1, 5, 25 g in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | >295 °C (subl.) (lit.) |
Storage Temp. | room temp |
UNSPSC | 12352200 |