D-Valine
SIGMA/V1255 - BioReagent, suitable for cell culture
Synonym: (R)-α-Aminoisovaleric acid; D-
CAS Number: 640-68-6
Empirical Formula (Hill Notation): C5H11NO2
Molecular Weight: 117.15
EC Number: 211-368-9
MDL Number: MFCD00064219
Linear Formula: (CH3)2CHCH(NH2)CO2H
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V1255-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V1255-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V1255-25G
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C5H11NO2/c1-3(2)4(6)5( |
| InChI key | KZSNJWFQEVHDMF-SCSAIBSYSA |
| mp | >295 °C (subl.) (lit.) |
| product line | BioReagent |
| Quality Level | 200  |
| shipped in | ambient |
| SMILES string | CC(C)[C@@H](N)C(O)=O |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| Application: | • Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture • endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture • DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture |
| Biochem/physiol Actions: | |
| Biochem/physiol Actions: | D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells. |
| General description: | L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine. |
| Packaging: | 1, 5, 25 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | >295 °C (subl.) (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12352209 |