[deamino-Pen¹, O-Me-Tyr², Arg⁸]-Vasopressin

SIGMA/V1880 - ≥97% (HPLC)

CAS Number: 67269-08-3
Empirical Formula (Hill Notation): C₄₉H₇₀N₁₄O₁₂S₂
Molecular Weight: 1111.30
MDL Number: MFCD00076745
Linear Formula: C₄₉H₇₀N₁₄O₁₂S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-V1880-1MG	1 mg	$170.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
form	powder
InChI	1S/C49H70N14O12S2/c1-49(2)24-40(67)57-32(22-28-13-15-29(75-3)16-14-28)43(70)60-33(21-27-9-5-4-6-10-27)44(71)58-31(17-18-37(50)64)42(69)61-34(23-38(51)65)45(72)62-35(26-76-77-49)47(74)63-20-8-12-36(63)46(73)59-30(11-7-19-55-48(53)54)41(68)56-25-39(52)66/h4-6,9-10,13-16,30-36H,7-8,11-12,17-26H2,1-3H3,(H2,50,64)(H2,51,65)(H2,52,66)(H,56,68)(H,57,67)(H,58,71)(H,59,73)(H,60,70)(H,61,69)(H,62,72)(H4,53,54,55)
InChI key	HNOGCDKPALYUIG-UHFFFAOYSA-N
Quality Level	200
shipped in	ambient
SMILES string	COc1ccc(CC2NC(=O)CC(C)(C)SSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(Cc3ccccc3)NC2=O)C(=O)N4CCCC4C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O)cc1
solubility	water: 0.5 mg/mL, clear, colorless
sterility	non-sterile
storage temp.	−20°C

Amino Acid Sequence:	3-Mercapto-3-methylbutyryl-Tyr-OMet-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]
Application:	[Deamino-Pen1, O-Me-Tyr2, Arg8]-Vasopressin was used to inhibit the V1 receptor, and study the role of arginine vasopressin receptors V1 and V2 on brain damage, brain edema formation and functional outcome after transient focal cerebral ischemia.
Biochem/physiol Actions:	[Deamino-Pen1, O-Me-Tyr2, Arg8]-Vasopressin is a V1 antagonist that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It also stimulates three acid-base transporters and hence increases the capability of the cell to regulate pHi.
Packaging:	1 mg in serum bottle
Preparation Note:	[deamino-Pen1, O-Me-Tyr2, Arg8]-Vasopressin dissolves in water at 0.5 mg/ml to yield a clear, colorless solution.

Symbol	GHS07
Signal word	Warning
Hazard statements	H332
Precautionary statements	P304 + P340 + P312
Hazard Codes	Xn
Risk Statements	20
Safety Statements	36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	51111800

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