Vancomycin hydrochloride from Streptomyces orientalis

SIGMA/V2002 - ≥900 μg per mg (as vancomycin base)

Synonym: Vancomycin HCL

CAS Number: 1404-93-9
Empirical Formula (Hill Notation): C₆₆H₇₅Cl₂N₉O₂₄ · HCl
Molecular Weight: 1485.71
Linear Formula: C₆₆H₇₅Cl₂N₉O₂₄ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-V2002-100MG	100 mg	$52.20 1/EA	Add To Favorites
45-V2002-250MG	250 mg	$97.90 1/EA	Add To Favorites
45-V2002-1G	1 g	$200.00 1/EA	Add To Favorites
45-V2002-5G	5 g	$789.00 1/EA	Add To Favorites
45-V2002-100G	100 g	$6250.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V2002-5G

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-positive bacteria
biological source	Streptomyces orientalis
color	, off-white to brown or White to orange-brown
concentration	≥900 μg/mg (as vancomycin base)
form	powder
mode of action	cell wall synthesis \| interferes
Quality Level	200
SMILES string	Cl[H].CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]2C[C@](C)(N)[C@@H](O)[C@@H](C)O2.CN[C@H](CC(C)C)C(=O)NC3[C@H](O)c4ccc(Oc5cc6Oc7ccc(cc7Cl)[C@@H](O)[C@H]8NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC3=O)c(c5)c6)c9ccc(O)c(c9)-c%10c(O)cc(O)cc%10[C@@H](NC8=O)C(O)=O)c(Cl)c4
storage condition	(Keep container tightly closed in a dry and well-ventilated place.)
storage temp.	2-8°C

Application:	Vancomycin, from Streptomyces orientalis, is used for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (β-lactam-resistant) staphylococci. It is used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It is widely studied in cancer patients. Vancomycin′s overuse has been studied, which has resulted in recommended guidelines.
Biochem/physiol Actions:	Glycopeptide antibiotic Mode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Antimicrobial spectrum: Gram-positive bacteria
Biochem/physiol Actions:	Vancomycin is a glycopeptide antibiotic that blocks bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. It is effective against Gram-positive bacteria. Vancomycin also alters bacterial-cell-membrane permeability and RNA synthesis.
General description:	Chemical structure: glycopeptide
Other Notes:	Keep container tightly closed in a dry and well-ventilated place.
Packaging:	1, 5 g in glass bottle
Packaging:	100, 250 mg in glass bottle
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Symbol	GHS08
Signal word	Danger
Hazard statements	H317 - H334
Precautionary statements	P261 - P272 - P280 - P284 - P302 + P352 - P304 + P340 + P312
Hazard Codes	Xi
Risk Statements	43
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	51101500

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