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Vinorelbine ditartrate salt hydrate

SIGMA/V2264 - ≥98% (HPLC), powder

Synonym: 3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine [R-(R*,R*)-2-3-dihydroxybutanedioate (1:2)salt]; 5′-Noranhydrovinoblastine tartrate; KW-2307; NVB; Navelbine tartrate

CAS Number: 125317-39-7 (anhydrous)
Empirical Formula (Hill Notation): C45H54N4O8 · 2C4H6O6 · xH2O
Molecular Weight: 1079.11 (anhydrous basis)
MDL Number: MFCD03613607
Linear Formula: C45H54N4O8 · 2C4H6O6 · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-V2264-5MG 5 mg
 $117.00
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assay ≥98% (HPLC)
color off-white
form powder
InChI 1S/C45H54N4O8.2C4H6O6.H2O/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7;2*5-1(3(7)8)2(6)4(9)10;/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3;2*1-2,5-6H,(H,7,8)(H,9,10);1H2/t28-,37-,38+,39+,42+,43+,44-,45-;2*1-,2-;/m011./s1
InChI key ZLIPKSVXTCRHIB-GNBHHJMASA-N
originator Pierre Fabre
Quality Level 100 
shipped in wet ice
SMILES string [H]O[H].O[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.[H][C@]12C[N@H](CC(CC)=C1)Cc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@]7([H])[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@]89[H])C(=O)OC
solubility H2O: 10 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: Potent anti-mitotic, anti-tumor agent; inhibits microtubule assembly.
Biochem/physiol Actions: Vinorelbine is a potent anti-mitotic, anti-tumor agent. Vinorelbine inhibits microtubule assembly. Low neurotoxicity is related to its higher affinity for mitotic microtubules than for axonal microtubules.
Features and Benefits: This compound was developed by Pierre Fabre . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H317
Precautionary statements P280
Hazard Codes Xi
Risk Statements 43
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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