Synonym: 3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine [R-(R*,R*)-2-3-dihydroxybutanedioate (1:2)salt]; 5′-Noranhydrovinoblastine tartrate; KW-2307; NVB; Navelbine tartrate
CAS Number: 125317-39-7 (anhydrous)
Empirical Formula (Hill Notation): C45H54N4O8 · 2C4H6O6 · xH2O
Molecular Weight: 1079.11 (anhydrous basis)
MDL Number: MFCD03613607
Linear Formula: C45H54N4O8 · 2C4H6O6 · xH2O
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
off-white |
| form |
powder |
| InChI |
1S/C45H54N4O8.2C4H6O6.H2O/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7;2*5-1(3(7)8)2(6)4(9)10;/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3;2*1-2,5-6H,(H,7,8)(H,9,10);1H2/t28-,37-,38+,39+,42+,43+,44-,45-;2*1-,2-;/m011./s1 |
| InChI key |
ZLIPKSVXTCRHIB-GNBHHJMASA-N |
| originator |
Pierre Fabre |
| Quality Level |
100  |
| shipped in |
wet ice |
| SMILES string |
[H]O[H].O[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.[H][C@]12C[N@H](CC(CC)=C1)Cc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@]7([H])[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@]89[H])C(=O)OC |
| solubility |
H2O: 10 mg/mL |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
Vinorelbine is a potent anti-mitotic, anti-tumor agent. Vinorelbine inhibits microtubule assembly. Low neurotoxicity is related to its higher affinity for mitotic microtubules than for axonal microtubules. |
| Features and Benefits: |
This compound was developed by Pierre Fabre . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: |
5 mg in glass bottle |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H317 |
| Precautionary statements |
P280 |
| Hazard Codes |
Xi |
| Risk Statements |
43 |
| Safety Statements |
26-36 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
