Advanced Search



Virginiamycin M1

SIGMA/V2753 - ≥95% (HPLC)

Synonym: Ostreogrycin A; Pristinamycin IIA; Staphylomycin M1; Streptogramin A; Virginiamycin M1; Mikamycin A; Staphylomycin

CAS Number: 21411-53-0
Empirical Formula (Hill Notation): C28H35N3O7
Molecular Weight: 525.59
EC Number: 244-376-6
MDL Number: MFCD00869411
Linear Formula: C28H35N3O7
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-V2753-5MG 5 mg
 $574.00
1/EA		 Add To Favorites
45-V2753-10MG 10 mg
 $1030.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum Gram-positive bacteria
assay ≥95% (HPLC)
biological source Streptomyces virginiae
color white to yellow
form powder
InChI 1S/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5-,10-9-,18-13-/t19-,20-,26-/m1/s1
InChI key DAIKHDNSXMZDCU-QHKJSJJMSA-N
mode of action protein synthesis | interferes
Quality Level 200 
SMILES string CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)C=C(C)C=CCNC(=O)C=C[C@H]1C)n3
solubility methanol: soluble 10 mg/mL
storage condition (Keep container tightly closed in a dry and well-ventilated place.)
storage temp. 2-8°C
Application: The antibiotic virginiamycin is produced by Streptomyces virginiae and is a member of the virginiamycin family. Each member is produced as a mixture of two structurally different compounds that exhibit synergistic antibacterial activity. There are two groups: virginiamycin M1 (VM1) and virginiamycin S (VS). VM1 is a polyunsaturated macrocyclic petolide. VM1 and VS are both used to inhibit protein synthesis since they are bacteriostatic. When used in combination they are more effective. Virginiamycin is used as a performance promoter in animal husbandry. They are chemically modified to make therapeutic drugs such as quinupristin and dalfopristin.
Biochem/physiol Actions: Virginiamycin M1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. S. virginiae inactivates VM1 by reducing its 16-carbonyl group, forming 16R-dihydroVM1. VM1 reductase participates solely in VM1 inactivation in vivo.
General description: Chemical structure: macrolide
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: 5, 10 mg in serum bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51101500

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top