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Vitamin B12

SIGMA/V2876 - ≥98%

Synonym: α-(5,6-Dimethylbenzimidazolyl)cyanocobamide; CN-Cbl; Cyanocob(III)alamin; Cyanocobalamin

CAS Number: 68-19-9
Empirical Formula (Hill Notation): C63H88CoN14O14P
Molecular Weight: 1355.37
EC Number: 200-680-0
Linear Formula: C63H88CoN14O14P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-V2876-100MG 100 mg
 $60.60
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45-V2876-250MG 250 mg
 $76.70
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45-V2876-500MG 500 mg
 $98.80
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45-V2876-1G 1 g
 $160.00
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45-V2876-5G 5 g
 $388.00
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45-V2876-25G 25 g
 $1870.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V2876-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V2876-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V2876-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V2876-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V2876-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V2876-5G

 

assay ≥98%
biological source synthetic (organic)
color red to brown
form powder
InChI 1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1
InChI key RMRCNWBMXRMIRW-QJRSUKKJSA-L
Quality Level 200 
SMILES string C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@
storage temp. 2-8°C
technique(s) HPLC: suitable
Application: Vitamin B12 has been used:
• as a constituent in vitamin mix solution in in vitro gut simulator
• as a standard in size exclusion inductively coupled plasma mass spectroscopy (SEC-ICP-MS)
• as a constituent of simulated plasma protein mixture for Raman spectra analysis
• in surface plasmon resonance (SPR) analysis
• as a medium supplement in neonatal rat ventricular myocytes (NRVM)
Biochem/physiol Actions: Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.
Packaging: 1, 5, 25 g in glass bottle
Packaging: 100, 250, 500 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Purity ≥98%
Storage Temp. 2-8°C
UNSPSC 12352200

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