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Vitamin B12

SIGMA/V6629 - BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

Synonym: α-(5,6-Dimethylbenzimidazolyl)cyanocobamide; CN-Cbl; Cyanocob(III)alamin; Cyanocobalamin

CAS Number: 68-19-9
Empirical Formula (Hill Notation): C63H88CoN14O14P
Molecular Weight: 1355.37
EC Number: 200-680-0
Linear Formula: C63H88CoN14O14P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-V6629-100MG 100 mg
 $58.00
1/EA		 Add To Favorites
45-V6629-250MG 250 mg
 $75.50
1/EA		 Add To Favorites
45-V6629-1G 1 g
 $180.00
1/EA		 Add To Favorites
45-V6629-5G 5 g
 $629.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V6629-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V6629-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V6629-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: V6629-5G

 

assay ≥98%
biological source microbial
color red to brown
form powder
InChI 1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1
InChI key RMRCNWBMXRMIRW-QJRSUKKJSA-L
mol wt Mw 1355.37 g/mol
pH 6
product line BioReagent
Quality Level 200 
SMILES string C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@
solubility water: soluble 50 mg/mL, dark red
storage temp. 2-8°C
technique(s) cell culture | insect: suitable
  cell culture | mammalian: suitable
  cell culture | plant: suitable
Application: Vitamin B12 has been used:
• as a component of Erdschreiber′s medium
• as a supplement of Dulbecco′s modified Eagle′s medium used for the isolation of ventricular myocytes from neonatal and adult rats
• orally administered to male quails to study its role in reducing the negative effects of sodium selenite intoxication, in vivo
Biochem/physiol Actions: Vitamin B12 is metabolized to its active form, methylcobalamin. Hindered vitamin B12 uptake is observed in pernicious anemia. Vitamin B12 is essential for erythroblast development. Pregnancy reduces the levels of vitamin B12. Aging reduces vitamin B12 absorption. It works as a coenzyme in fat, carbohydrate and protein metabolism. It is required for growth, genetic stability and survival of cells in vitro. Functions to support one-carbon metabolism. Present in many classical and serum-free formulations.
General description: Cyanocobalamin (B12) is a water soluble vitamin, commonly called as cobalamins. Dairy products, meat and eggs are the major sources of this vitamin.
Packaging: 1, 5 g in glass bottle
Packaging: 100, 250 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Purity ≥98%
Storage Temp. 2-8°C
UNSPSC 12352200

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