Venlafaxine hydrochloride
SIGMA/V7264 - ≥98% (HPLC), powder
Synonym: (+/
CAS Number: 99300-78-4
Empirical Formula (Hill Notation): C17H27NO2 · HCl
Molecular Weight: 313.86
MDL Number: MFCD03658865
Linear Formula: C17H27NO2 · HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white |
| form | powder |
| InChI | 1S/C17H27NO2.ClH/c1-18(2) |
| InChI key | QYRYFNHXARDNFZ-UHFFFAOYSA |
| originator | Wyeth |
| Quality Level | 100  |
| SMILES string | Cl[H].COc1ccc(cc1)C(CN(C) |
| solubility | H2O: >10 mg/mL |
| storage condition | desiccated |
| protect from light |
| Biochem/physiol Actions: | Venlafaxine is a dual serotonin-noradrenaline reuptake inhibitor that displays Ki values of 82 and 2480 nM respectively. It is a general class antidepressant. |
| Biochem/physiol Actions: | Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity. |
| Features and Benefits: | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Wyeth . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol |  GHS09 |
| Hazard statements | H411 |
| Precautionary statements | P273 - P391 - P501 |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352200 |