Violacein from Janthinobacterium lividum

SIGMA/V9389 - >98% (violacein (minimum 85% violacein) and deoxyviolacein, HPLC)

CAS Number: 548-54-9
Empirical Formula (Hill Notation): C₂₀H₁₃N₃O₃
Molecular Weight: 343.34
Linear Formula: C₂₀H₁₃N₃O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-V9389-1MG	1 mg	$440.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	>98% (violacein (minimum 85% violacein) and deoxyviolacein, HPLC)
InChI	1S/C20H13N3O3/c24-10-5-6-15-12(7-10)14(9-21-15)17-8-13(19(25)23-17)18-11-3-1-2-4-16(11)22-20(18)26/h1-9,21,24H,(H,22,26)(H,23,25)/b18-13-
InChI key	XAPNKXIRQFHCHN-AQTBWJFISA-N
Quality Level	200
solubility	acetone: soluble
	ethanol: soluble
	H₂O: insoluble
	methanol: soluble
storage temp.	2-8°C

Application:	Violacein from Janthinobacterium lividum has been used: • for cell culture assays • as a standard to determine the crude violacein concentration in ethanol extracts of D. violaceinigra str. NI28 cultures • as a standard to identify violacein in the leaf samples of Nicotiana
Biochem/physiol Actions:	Violacein, a violet pigment, is an indole derivative produced by various bacterial strains such as Chromobacterium violaceum, Janthinobacterium lividum, Chromobacterium lividum, and Pseudoalteromonas luteoviolacea. Violacein is a member of a novel class of cytotoxic drugs, which mediate apoptosis. Violacein exhibits antitumoral, antibacterial, antiulcerogenic, antileishmanial, and antiviral activities. Violacein and its β-cyclodextrin complexes trigger apoptosis and differentiation in HL60 leukemic cells. Violacein cytotoxicity is preceded by activation of caspase 8, transcription of NF-κB target genes, and p38-MAPK activation resembling TNF-α signal transduction.
General description:	Violacein from Janthinobacterium lividum is used as a colorant for natural and synthetic fabrics. It functions as a respiratory pigment and regulates tryptophan production. Violacein exhibits anti-protozoal activity.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	>98% (violacein (minimum 85% violacein) and deoxyviolacein, HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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