[Arg⁸]-Vasopressin acetate salt

SIGMA/V9879 - ≥95% (HPLC)

Synonym: β-Hypophamine; AVP; Antidiuretic hormone; Arginine vasopressin

CAS Number: 113-79-1
Empirical Formula (Hill Notation): C₄₆H₆₅N₁₅O₁₂S₂ · xC₂H₄O₂
Molecular Weight: 1084.23 (free base basis)
EC Number: 204-035-4
MDL Number: MFCD00133939
Linear Formula: C₄₆H₆₅N₁₅O₁₂S₂ · xC₂H₄O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-V9879-1MG	1 mg	$104.00 1/EA	Add To Favorites
45-V9879-5MG	5 mg	$358.00 1/EA	Add To Favorites
45-V9879-25MG	25 mg	$1520.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
biological source	synthetic (organic)
form	powder
InChI	1S/C46H65N15O12S2.C2H4O2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25;1-2(3)4/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53);1H3,(H,3,4)/t27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1
InChI key	ZHFGXNMADRRGQP-HPILINOVSA-N
Quality Level	200
shipped in	ambient
SMILES string	CC(O)=O.N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O
solubility	water: 20.0-20.8 mg/mL, clear, colorless to faintly yellow
sterility	non-sterile
storage temp.	−20°C
UniProt accession no.	P01185
	P30518
	P37288
	P47901

Amino Acid Sequence:	Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]
Application:	[Arg8]-Vasopressin acetate salt has been: • used as a vasopressin receptor agonist to test vasopressin receptors • used to evoke peripheral V1a receptor-mediated vasoconstriction • as a supplement in Ham′s F12/Dulbecco′s modified Eagle′s medium for proximal tubule and glomerular explant cell culture
Biochem/physiol Actions:	Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg⁸-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).
Biochem/physiol Actions:	Endogenous antidiuretic hormone in most mammalian species; neurotransmitter in the central nervous system implicated in a variety of physiological processes including diuresis, vasoregulation, and memory.
General description:	Arginine vasopressin is a nonapeptide. It is produced by anterior hypothalamus nerve cells.
Other Notes:	Lyophilized from 0.5% acetic acid
Preparation Note:	[Arg8]-Vasopressin acetate salt dissolves water at 20 mg/ml to yield a clear colorless to faint yellow solution.

Hazard Codes	Xn
Risk Statements	20
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	51111800

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