(R)-(+)-WIN 55,212-2 mesylate salt

SIGMA/W102 - ≥98% (HPLC)

Synonym: (R)-(+)-[2,3-Dihydro-5-methyl-3[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate salt; WIN 55212-2 methanesulfonate; WIN 552122 mesylate

CAS Number: 131543-23-2
Empirical Formula (Hill Notation): C₂₇H₂₆N₂O₃ · CH₄O₃S
Molecular Weight: 522.61
MDL Number: MFCD00153882
Linear Formula: C₂₇H₂₆N₂O₃ · CH₃SO₃H
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-W102-25MG	25 mg	$446.00 1/EA	Add To Favorites
45-W102-100MG	100 mg	$910.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: W102-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
drug control	regulated under CDSA - not available from Sigma-Aldrich Canada
form	powder
InChI	1S/C27H26N2O3.CH4O3S/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28;1-5(2,3)4/h2-11,20H,12-17H2,1H3;1H3,(H,2,3,4)/t20-;/m1./s1
InChI key	FSGCSTPOPBJYSX-VEIFNGETSA-N
Quality Level	100
SMILES string	CS(O)(=O)=O.Cc1c(C(=O)c2cccc3ccccc23)c4cccc5OC[C@@H](CN6CCOCC6)n1c45
solubility	0.1 M HCl: 0.25 mg/mL
	0.1 M NaOH: insoluble
	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.4 mg/mL
	DMSO: 12 mg/mL
	H₂O: insoluble

Application:	(R)-(+)-WIN 55,212-2 mesylate salt has been used as a high affinity cannabinoid agonist for intraperitoneal injection into rats to induce behavioural sensitization. It has also been used as a synthetic cannabinoid drug and cannabinoid receptor 1 (CNR1) agonist to treat Becn2+/− mice and wild-type (WT) littermate to analyze the levels of CNR1 in the brain.
Biochem/physiol Actions:	It is known to decrease the lipopolysaccharide mediated release of tumor necrosis factor- α and interleukin-1 in mice.
Features and Benefits:	This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description:	WIN 55,212-2 is a member of the aminoalkylindole class of compounds.
Legal Information:	Sold with the permission of Sterling-Winthrop, Inc.
Packaging:	100 mg in glass bottle
Packaging:	25 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
UNSPSC	12352200

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