W146 hydrate
SIGMA/W1020 - ≥98% (HPLC)
Synonym: ML056; R-
CAS Number: 909725-61-7 (anhydrous)
Empirical Formula (Hill Notation): C16H27N2O4P · xH2O
Molecular Weight: 342.37 (anhydrous basis)
MDL Number: MFCD16875441
Linear Formula: C16H27N2O4P · xH2O
Product Type: Chemical
assay | ≥98% (HPLC) |
color | off-white |
form | powder |
InChI | 1S/C16H27N2O4P.H2O/c1-2-3 |
InChI key | DQKSZHVSROOTFY-XFULWGLBSA |
originator | Novartis |
Quality Level | 100 |
SMILES string | O.CCCCCCc1cccc(NC(=O)[C@H |
solubility | methanol: soluble (with 0.1% TFA) |
storage temp. | 2-8°C |
Application: | W146 hydrate has been used to assess vascular permeability in mice. |
Biochem/physiol Actions: | Potent S1P(1) competitive antagonist; Ki = 10-77 nM. |
Features and Benefits: | This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Features and Benefits: | This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
General description: | W146 hydrate functions as an orthosteric antagonist. It is associated with blood lymphopenia and lung edema in mice. |
Packaging: | 1, 5 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352211 |