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WAY-100635 maleate salt

SIGMA/W108 - powder

Synonym: N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate salt

CAS Number: 634908-75-1
Empirical Formula (Hill Notation): C25H34N4O2 · C4H4O4
Molecular Weight: 538.64
MDL Number: MFCD01321056
Linear Formula: C25H34N4O2 · C4H4O4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-W108-5MG 5 mg
$327.00
1/EA
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45-W108-25MG 25 mg
$1130.00
1/EA
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color white
form powder
InChI 1S/C25H34N4O2.C4H4O4/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21;5-3(6)1-2-4(7)8/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key XIGAHNVCEFUYOV-BTJKTKAUSA-N
Quality Level 100 
SMILES string [H]C(=C(/[H])C(O)=O)C(O)=O.COc1ccccc1N2CCN(CC2)CCN(C(=O)C3CCCCC3)c4ccccn4
solubility H2O: 25 mg/mL
Application: WAY-100635 maleate salt has been used as a 5-HT1A serotonin receptor antagonist:
• to study whether the behavior of the cleaner wrasse is regulated by serotonin activity
• to block activity of 3,4 methylenedioxymethamphetamine (MDMA) used to induce oxytocin release in male Wistar rats to increase their social behavior
• to study the role of serotonin during metamorphosis of the ascidian Phallusia mammillata larvae

Biochem/physiol Actions: WAY-100635 maleate salt is a highly selective 5-HT1A serotonin receptor antagonist. It has an ability to inhibit brexpiprazole, an antipsychotic drug that regulates serotonin-dopamine activity.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 12352200

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