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WAY-200070

SIGMA/W1520 - ≥98% (HPLC)

Synonym: 7-Bromo-2-(4-hydroxyphenyl)-1,3-benzoxazol-5-ol; 7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol

CAS Number: 440122-66-7
Empirical Formula (Hill Notation): C13H8BrNO3
Molecular Weight: 306.11
MDL Number: MFCD16618385
Linear Formula: C13H8BrNO3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-W1520-5MG 5 mg
$115.00
1/EA
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45-W1520-25MG 25 mg
$441.00
1/EA
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assay ≥98% (HPLC)
form solid
InChI 1S/C13H8BrNO3/c14-10-5-9(17)6-11-12(10)18-13(15-11)7-1-3-8(16)4-2-7/h1-6,16-17H
InChI key BAAILVWEAXFTSF-UHFFFAOYSA-N
originator Wyeth
Quality Level 100 
SMILES string Oc1ccc(cc1)-c2nc3cc(O)cc(Br)c3o2
solubility DMSO: ≥20 mg/mL
storage temp. 2-8°C
Application: WAY-200070, a selective estrogen receptor-beta (ER-β) agonist, may be used in estrogen receptor signaling research along with other ERβ agonists [diarylpropionitrile (DPN)] and antagonist to help identify and differentiate the functions of estrogen receptor-beta(s) (ER-β) involved in processes such as regulation of the physiology of the endocrine pancreas; modulation of visceral pain; and stress response. WAY-200070 may be used to help establish that an observed physiological or cell signaling response is ER-β-dependent, especially versus ERα.
Biochem/physiol Actions: Potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.
Features and Benefits: This compound was developed by Wyeth . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: WAY-200070 is a potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs. 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51111800

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