1400W dihydrochloride
SIGMA/W4262 - >98%, solid
Synonym: N-
CAS Number: 214358-33-5
Empirical Formula (Hill Notation): C10H15N3 · 2 HCl
Molecular Weight: 250.17
MDL Number: MFCD03428622
Linear Formula: C10H15N3 · 2 HCl
Product Type: Chemical
| assay | >98% |
| form | solid |
| InChI | 1S/C10H15N3.2ClH/c1-8(12) |
| InChI key | WDJHSQZCZGPGAA-UHFFFAOYSA |
| originator | GlaxoSmithKline |
| Quality Level | 100  |
| shipped in | wet ice |
| SMILES string | Cl[H].Cl[H].CC(=N)NCc1ccc |
| storage condition | desiccated |
| storage temp. | −20°C |
| Application: | 1400W dihydrochloride has been used: • as a strong inhibitor of inducible nitric oxide to analyse its effect on intestinal ischemia/reperfusion (I/R) injury model in rat • as inducible nitric oxide synthase (iNOS)-selective inhibitor, to elucidate the mechanism of PM10-induced endothelial dysfunction • to study its efficacy on renal ischemia/ reperfusion injury in rats • as iNOS inhibitor to investigate its ability to counteract spatial memory deficits after hypobaric hypoxia reoxygenation |
| Biochem/physiol Actions: | 1400W dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS). |
| Features and Benefits: | This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 10 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >98% |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |