Monoclonal Anti-CD3E antibody produced in mouse
SIGMA/WH0000916M4 - clone 4C1, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CD3E antigen, epsilon polypeptide (TiT3 complex); Anti-T3E; Anti-TCRE
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 4C1, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | BC049847 |
isotype | IgG2aκ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | mouse, human, rat |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
proximity ligation assay: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | P07766 |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. (provided by RefSeq) |
Immunogen: | CD3E (AAH49847.1, 23 a.a. ~ 207 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence DGNEEMGGITQTPYKVSISGTTVIL |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |