Monoclonal Anti-DMRT1 antibody produced in mouse
SIGMA/WH0001761M1 - clone 1G11, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-DMT1; Anti-doublesex and mab-3 related transcription factor 1
Product Type: Chemical
Western Blotting Western Blot analysis of DMRT1 expression in transfected 293T cell line by DMRT1 monoclonal antibody, clone 1G11. Lanes Lane 1: DMRT1 transfected lysate (39.5 kDa). Lane 2: Non-transfected lysate.
Western Blotting DMRT1 monoclonal antibody, clone 1G11 Western Blot analysis of DMRT1 expression in HL-60.
Western Blotting QC Western Blot detection against Immunogen (66.77 kDa).
ELISA Detection limit for recombinant GST tagged DMRT1 is approximately 0.3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1G11, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | BC040847   |
| isotype | IgG1κ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9Y5R6 |
| General description: | This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. (provided by RefSeq) |
| Immunogen: | DMRT1 (AAH40847.1, 1 a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MPNDEAFSKPSTPSEAPHAPGVPPQ |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |