Monoclonal Anti-DSCR1 antibody produced in mouse
SIGMA/WH0001827M1 - clone 1G7, ascites fluid
Synonym: Anti-ADAPT78; Anti-CSP1; Anti-DSC1; Anti-Down syndrome critical region gene 1; Anti-MCIP1; Anti-RCN1
Product Type: Chemical
antibody form | ascites fluid |
antibody product type | primary antibodies |
biological source | mouse |
clone | 1G7, monoclonal |
conjugate | unconjugated |
GenBank® accession no. | BC002864 |
isotype | IgG1κ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1:500-1:1000 | |
UniProt accession no. | P53805 |
General description: | The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. (provided by RefSeq) |
Immunogen: | DSCR1 (AAH02864, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MEEVDLQDLPSATIACHLDPRVFVD |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |