Monoclonal Anti-ECHS1 antibody produced in mouse
SIGMA/WH0001892M1 - clone 1G9, ascites fluid
Synonym: Anti-SCEH; Anti-enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
Product Type: Chemical
Western Blotting QC Western Blot detection against Immunogen (56.32 kDa).
Immunoprecipitation Immunoprecipitation of ECHS1 transfected lysate using anti-ECHS1 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with ECHS1 rabbit polyclonal antibody.
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1G9, monoclonal |
| conjugate | unconjugated |
| GenBank accession no. | BC008906   |
| isotype | IgMκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoprecipitation (IP): suitable |
| indirect ELISA: suitable | |
| UniProt accession no. | P30084 |
| Biochem/physiol Actions: | ECHS1 (Enoyl CoA hydratase, short chain 1, mitochondrial) performs in the mitochondrial β-oxidation of fatty acid by catalyzing the second step of the process i.e. hydration of 2-trans-enoyl-coenzyme A (CoA) to L-3-hydroxyacyl-CoAs. It also participates in different metabolic pathways involving fatty acids and amino acids, valine. Study reports that heterozygous mutation in ECHS1 causes Leigh syndrome with hypotonia, metabolic acidosis, and developmental delay symptoms. |
| Immunogen: | ECHS1 (AAH08906, 13 a.a. ~ 290 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence GPLRPPVRCPAWRPFASGANFEYII |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |