Monoclonal Anti-ERN1 antibody produced in mouse
SIGMA/WH0002081M2 - clone 8D12, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-FLJ30999; Anti-IRE1; Anti-IRE1P; Anti-endoplasmic reticulum to nucleus signalling 1
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 8D12, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | AF059198 ![]() ![]() |
isotype | IgG2aκ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
indirect immunofluorescence: suitable | |
proximity ligation assay: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | O75460 ![]() ![]() |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. (provided by RefSeq) |
Immunogen: | ERN1 (AAC25991, 401 a.a. ~ 500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence EEVINLVDQTSENAPTTVSRDVEEK |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |