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Monoclonal Anti-FGR antibody produced in mouse

SIGMA/WH0002268M1 - clone 3G10, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; Anti-SRC2; Anti-cfgr; Anti-p55cfgr

MDL Number: MFCD02686140
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-WH0002268M1-100UG 100 µg
$524.00
1/EA
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Immunohistochemistry Immunoperoxidase of monoclonal antibody to FGR on formalin-fixed paraffin-embedded human lymph node. [antibody concentration 3 μg/mL]
Western Blotting FGR monoclonal antibody, clone 3G10 Western Blot analysis of FGR expression in HeLa.
Western Blotting FGR monoclonal antibody, clone 3G10. Western Blot analysis of FGR expression in Raw 264.7.
Western Blotting FGR monoclonal antibody, clone 3G10. Western Blot analysis of FGR expression in PC-12.
Western Blotting QC Western Blot detection against Immunogen (35.53 kDa).
ELISA Detection limit for recombinant GST tagged FGR is approximately 0.3 ng/mL as a capture antibody.

 

antibody form purified immunoglobulin
antibody product type primary antibodies
biological source mouse
clone 3G10, monoclonal
conjugate unconjugated
form buffered aqueous solution
GenBank® accession no. BC064382 
isotype IgG2aκ
Quality Level 100 
shipped in dry ice
species reactivity mouse, human, rat
storage temp. −20°C
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  indirect ELISA: suitable
  western blot: 1-5 μg/mL
UniProt accession no. P09769 
General description: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. (provided by RefSeq)
Immunogen: FGR (AAH64382, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEA
Legal Information: GenBank is a registered trademark of United States Department of Health and Human Services
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR NONH for all modes of transport
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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