Monoclonal Anti-FXN antibody produced in mouse
SIGMA/WH0002395M3 - clone 3G9, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-FA; Anti-FARR; Anti-FRDA; Anti-MGC57199; Anti-X25; Anti-frataxin
MDL Number: MFCD02262922
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 3G9, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_000144 ![]() ![]() |
isotype | IgG1κ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1-5 μg/mL | |
UniProt accession no. | Q16595 ![]() ![]() |
Biochem/physiol Actions: | Frataxin (FXN) is involved in the activation of iron-sulfur cluster assembly.Overexpression of FXN in reticulocytes is associated with oxidative stress and iron status.Deficiency of FXN in human astrocytes is linked to cell death and release of neurotoxins. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | Frataxin (FXN) protein consists of α/β fold, which is followed by the C-terminal region (CTR), with a nonperiodic structure.The gene is located on human chromosome 9q21.11. |
Immunogen: | FXN (AAH48097.1, 91 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence DETTYERLAEETLDSLAEFFEDLAD |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |