Monoclonal Anti-GLI3 antibody produced in mouse
SIGMA/WH0002737M1 - clone 2C9, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-ACLS; Anti-GCPS; Anti-GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome); Anti-PAPA; Anti-PAPA1; Anti-PAPB; Anti-PHS; Anti-PPDIV
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 2C9, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_000168 ![]() ![]() |
isotype | IgG2aκ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | immunofluorescence: suitable |
indirect ELISA: suitable | |
proximity ligation assay: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | P10071 ![]() ![]() |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. (provided by RefSeq) |
Immunogen: | GLI3 (NP_000159, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MEAQSHSSTTTEKKKVENSIVKCST |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |