Monoclonal Anti-HSD11B1 antibody produced in mouse
SIGMA/WH0003290M2 - clone 2C10, ascites fluid
Synonym: Anti-11DH; Anti-11betaHSD1; Anti-HDL; Anti-HSD11; Anti-HSD11B; Anti-HSD11L; Anti-MGC13539; Anti-hydroxysteroid (11-beta) dehydrogenase 1
MDL Number: MFCD08064405
Product Type: Chemical
Western Blotting HSD11B1 monoclonal antibody, clone 2C10. Western Blot analysis of HSD11B1 expression in human liver.
Western Blotting HSD11B1 monoclonal antibody, clone 2C10. Western Blot analysis of HSD11B1 expression in MCF-7.
Western Blotting Western Blot analysis of HSD11B1 expression in transfected 293T cell line by HSD11B1 monoclonal antibody, clone 2C10. Lanes Lane 1: HSD11B1 transfected lysate (Predicted MW: 32.4 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (57.86 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2C10, monoclonal |
| conjugate | unconjugated |
| GenBank® accession no. | BC012593   |
| isotype | IgMκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P28845 |
| General description: | The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. (provided by RefSeq) |
| Immunogen: | HSD11B1 (AAH12593, 1 a.a. ~ 292 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MAFMKKYLLPILGLFMAYYYYSANE |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |