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Monoclonal Anti-ICAM3 antibody produced in mouse

SIGMA/WH0003385M1 - clone 2F8, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-CD50; Anti-CDW50; Anti-ICAMR; Anti-intercellular adhesion molecule 3

MDL Number: MFCD01092375
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-WH0003385M1-100UG 100 µg
$0.00
1/EA
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Immunohistochemistry Immunoperoxidase of monoclonal antibody to ICAM3 on formalin-fixed paraffin-embedded human stomach carcinoma tissue. [antibody concentration 3 μg/mL]
Western Blotting ICAM3 monoclonal antibody, clone 2F8 Western Blot analysis of ICAM3 expression in HL-60.
Western Blotting QC Western Blot detection against Immunogen (82.72 kDa).

 

antibody form purified immunoglobulin
antibody product type primary antibodies
biological source mouse
clone 2F8, monoclonal
conjugate unconjugated
form buffered aqueous solution
GenBank® accession no. BC058903 
isotype IgG2bκ
Quality Level 100 
shipped in dry ice
species reactivity human
storage temp. −20°C
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  indirect ELISA: suitable
  western blot: 1-5 μg/mL
UniProt accession no. P32942 
General description: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. (provided by RefSeq)
Immunogen: ICAM3 (AAH58903, 30 a.a. ~ 547 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMGEEPSRAE
Legal Information: GenBank is a registered trademark of United States Department of Health and Human Services
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR NONH for all modes of transport
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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