Monoclonal Anti-ICAM3 antibody produced in mouse
SIGMA/WH0003385M1 - clone 2F8, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CD50; Anti-CDW50; Anti-ICAMR; Anti-intercellular adhesion molecule 3
MDL Number: MFCD01092375
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 2F8, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | BC058903 |
isotype | IgG2bκ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
indirect ELISA: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | P32942 |
General description: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. (provided by RefSeq) |
Immunogen: | ICAM3 (AAH58903, 30 a.a. ~ 547 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence QEFLLRVEPQNPVLSAGGSLFVNCS |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |