Monoclonal Anti-IL2 antibody produced in mouse
SIGMA/WH0003558M3 - clone 3C8, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-IL2; Anti-TCGF; Anti-interleukin 2; Anti-lymphokine
MDL Number: MFCD00675261
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 3C8, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | N/A ![]() ![]() |
isotype | IgG2aκ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
UniProt accession no. | P60568 ![]() ![]() |
Biochem/physiol Actions: | Interleukin 2 (IL2) promotes the development of suppressor T regulatory cells. IL2 plays a crucial role in antitumor immunity. IL2 destabilises adherens junctions, and cytoskeletal reorganization, causing increased endothelial cell permeability. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | Interleukin 2 (IL2) is synthesised by immunoregulatory T helper cells. IL2 consists of three subunits, in which the beta subunit is critical for receptor mediated signalling. IL2 gene is located on human chromosome 4q27. |
Immunogen: | IL2 (NP_000577, 21 a.a. ~ 153 a.a) recombinant protein. Sequence MAPTSSSTKKTQLQLEHLLLDLQMI |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |