Monoclonal Anti-JUP antibody produced in mouse
SIGMA/WH0003728M1 - clone 2G9, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CTNNG; Anti-DP3; Anti-DPIII; Anti-PDGB; Anti-PKGB; Anti-junction plakoglobin
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of monoclonal antibody to JUP on formalin-fixed paraffin-embedded human lymphoma tissue. [antibody concentration 3 μg/mL]
Immunofluorescence Immunofluorescence of monoclonal antibody to JUP on A-431 cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of JUP expression in transfected 293T cell line by JUP monoclonal antibody, clone 2G9. Lanes Lane 1: JUP transfected lysate (81.7 kDa). Lane 2: Non-transfected lysate.
Western Blotting JUP monoclonal antibody, clone 2G9 Western Blot analysis of JUP expression in A-431.
Western Blotting QC Western Blot detection against Immunogen (107.69 kDa).
ELISA Detection limit for recombinant GST tagged JUP is approximately 1 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2G9, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | BC011865   |
| isotype | IgGκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| indirect ELISA: suitable | |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | P14923 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. (provided by RefSeq) |
| Immunogen: | JUP (AAH11865.1, 1 a.a. ~ 745 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MEVMNLMEQPIKVTEWQQTYTYDSG |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |