Monoclonal Anti-KRTHB1 antibody produced in mouse
SIGMA/WH0003887M1 - clone 3B10-5B10, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-HB1; Anti-Hb1; Anti-MLN137; Anti-ghHkb1; Anti-hHAKB21; Anti-keratin, hair, basic, 1
MDL Number: MFCD04975341
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of monoclonal antibody to KRTHB1 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 μg/mL]
Immunofluorescence Immunofluorescence of monoclonal antibody to KRTHB1 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting KRTHB1 monoclonal antibody, clone 3B10-5B10 Western Blot analysis of KRTHB1 expression in HepG2.
Western Blotting QC Western Blot detection against Immunogen (47.96 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3B10-5B10, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | BC021241   |
| isotype | IgG2bκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| indirect ELISA: suitable | |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q14533 |
| General description: | The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. (provided by RefSeq) |
| Immunogen: | KRTHB1 (AAH21241, 1 a.a. ~ 202 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MKATVIRHGETLRRTKEEINELNRM |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |