Monoclonal Anti-MAZ antibody produced in mouse
SIGMA/WH0004150M1 - clone 3D2, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-MYC-associated zinc finger protein (purine-binding transcription factor); Anti-PUR1; Anti-Pur1; Anti-SAF1; Anti-SAF2; Anti-ZF87; Anti-Zif87
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 3D2, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_002383 |
isotype | IgG2bκ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
indirect immunofluorescence: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | P56270 |
Biochem/physiol Actions: | MYC associated zinc finger protein (MAZ) controls various inflammation-responsive genes. It plays a major role in the development of AA amyloidosis (amyloid A amyloidosis), a consequence of chronic inflammation. MAZ controls transcriptional initiation and termination by binding to c-MYC and C2 gene sequences. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | MYC associated zinc finger protein (MAZ) is also known as SAF-1 (serum amyloid A activating factor 1) and Pur-1 (purine binding factor-1). It is a member of the the family of Cys2-His2 type zinc fingers. This gene is mapped to human chromosome 16p11. |
Immunogen: | MAZ (NP_002374, 332 a.a. ~ 440 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence YQCPVCQQRFKRKDRMSYHVRSHDG |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |