Monoclonal Anti-MCM3 antibody produced in mouse
SIGMA/WH0004172M1 - clone 4F7, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-HCC5; Anti-MCM3 minichromosome maintenance deficient 3 (S. cerevisiae); Anti-MGC1157; Anti-P1.h; Anti-P1MCM3; Anti-RLFB
MDL Number: MFCD02263436
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 4F7, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_002388 ![]() ![]() |
isotype | IgG2aλ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | mouse |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
indirect immunofluorescence: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | P25206 ![]() ![]() |
General description: | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. (provided by RefSeq) |
Immunogen: | MCM3 (NP_002379, 699 a.a. ~ 808 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence AKDGDSYDPYDFSDTEEEMPQVHTP |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |