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Monoclonal Anti-HNRPM antibody produced in mouse

SIGMA/WH0004670M3 - clone 3F7, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-DKFZp547H118; Anti-HNRNPM; Anti-HNRNPM4; Anti-HNRPM4; Anti-HTGR1; Anti-NAGR1; Anti-heterogeneous nuclear ribonucleoprotein M

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-WH0004670M3-100UG 100 µg
$0.00
1/EA
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Immunohistochemistry Immunoperoxidase of monoclonal antibody to HNRPM on formalin-fixed paraffin-embedded human thyroid nodular goiter. [antibody concentration 3 μg/mL]
Immunofluorescence Immunofluorescence of monoclonal antibody to HNRPM on HepG2 cell. [antibody concentration 10 μg/mL]
Western Blotting HNRPM monoclonal antibody, clone 3F7. Western Blot analysis of HNRPM expression in NIH/3T3.
Western Blotting HNRPM monoclonal antibody, clone 3F7 Western Blot analysis of HNRPM expression in HepG2.
Western Blotting HNRPM monoclonal antibody, clone 3F7. Western Blot analysis of HNRPM expression in PC-12.
Western Blotting QC Western Blot detection against Immunogen (36.3 kDa).
ELISA Detection limit for recombinant GST tagged HNRPM is approximately 0.1 ng/mL as a capture antibody.

 

antibody form purified immunoglobulin
antibody product type primary antibodies
biological source mouse
clone 3F7, monoclonal
conjugate unconjugated
form buffered aqueous solution
GenBank® accession no. NM_005968 
isotype IgG2aκ
Quality Level 100 
shipped in dry ice
species reactivity rat, human, mouse
storage temp. −20°C
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  indirect ELISA: suitable
  indirect immunofluorescence: suitable
  western blot: 1-5 μg/mL
UniProt accession no. P52272 
General description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated. (provided by RefSeq)
Immunogen: HNRPM (NP_005959, 17 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
KMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSR
Legal Information: GenBank is a registered trademark of United States Department of Health and Human Services
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR NONH for all modes of transport
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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