Monoclonal Anti-NBN antibody produced in mouse
SIGMA/WH0004683M1 - clone 3E4, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-ATV; Anti-ATV1; Anti-ATV2; Anti-MGC87362; Anti-NBS; Anti-NBS1; Anti-nibrin
MDL Number: MFCD03455620
Product Type: Chemical
Western Blotting NBN monoclonal antibody, clone 3E4 Western Blot analysis of NBN expression in COLO 320 HSR.
Western Blotting NBN monoclonal antibody, clone 3E4 Western Blot analysis of NBN expression in HL-60.
Western Blotting QC Western Blot detection against Immunogen (37.84 kDa).
ELISA Detection limit for recombinant GST tagged NBN is approximately 3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3E4, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | NM_002485   |
| isotype | IgG2aκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O60934 |
| General description: | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. (provided by RefSeq) |
| Immunogen: | NBN (NP_002476, 645 a.a. ~ 754 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence DDSEMLPKKLLLTEFRSLVIKNSTS |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |