Monoclonal Anti-PKM2 antibody produced in mouse
SIGMA/WH0005315M1 - clone 5D2-3B3, ascites fluid
Synonym: Anti-CTHBP; Anti-MGC3932; Anti-OIP3; Anti-PK3; Anti-PKM; Anti-TCB; Anti-THBP1; Anti-pyruvate kinase, muscle
Product Type: Chemical
antibody form | ascites fluid |
antibody product type | primary antibodies |
biological source | mouse |
clone | 5D2-3B3, monoclonal |
conjugate | unconjugated |
GenBank® accession no. | BC007640 |
isotype | IgMκ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1:500-1:1000 |
Application: | Monoclonal Anti-PKM2 antibody has been used in western blotting. |
Biochem/physiol Actions: | The embryonic pyruvate kinase M2 (PKM2) controls β-catenin transactivation. It plays an important role in aerobic glycolysis or the warburg effect. PKM2 induce gene transcription and tumorigenesis. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | The embryonic pyruvate kinase M2 (PKM2) is one of the isoforms of pyruvate kinases (PK), found in mammals. It is coded by the PKM2 gene mapped to human chromosome 15q23. PKM2 is expressed in all cells excluding adult muscle, brain and liver. This protein is usually present as an active tetrameric form. |
Immunogen: | PKM2 (AAH07640.1, 1 a.a. ~ 531 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MSKPHSEAGTAFIQTQQLHAAMADT |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |