Monoclonal Anti-PLAGL1 antibody produced in mouse
SIGMA/WH0005325M1 - clone 1E2, ascites fluid
Synonym: Anti-DKFZp781P1017; Anti-LOT1; Anti-ZAC; Anti-ZAC1; Anti-pleiomorphic adenoma gene-like 1
Product Type: Chemical
antibody form | ascites fluid |
antibody product type | primary antibodies |
biological source | mouse |
clone | 1E2, monoclonal |
conjugate | unconjugated |
GenBank® accession no. | NM_002656 |
isotype | IgMκ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1:500-1:1000 | |
UniProt accession no. | Q9UM63 |
Biochem/physiol Actions: | The maternally-imprinted gene, PLAGL1 (pleiomorphic adenoma-like protein 1), functions as an oncogene as well as a tumor suppressor depending on the cell context. It has been found to exhibit anti-proliferative properties and regulate apoptosis and cell-cycle arrest via p53. |
General description: | This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Many transcript variants encoding two different isoforms have been found for this gene. (provided by RefSeq) |
Immunogen: | PLAGL1 (NP_002647.2, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence QPMQPLPESLASLHPSVSPGSPPPP |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |