Monoclonal Anti-PLAGL1 antibody produced in mouse
SIGMA/WH0005325M1 - clone 1E2, ascites fluid
Synonym: Anti-DKFZp781P1017; Anti-LOT1; Anti-ZAC; Anti-ZAC1; Anti-pleiomorphic adenoma gene-like 1
Product Type: Chemical
Immunoblotting Monoclonal Anti-PLAGL1, Cat. No. WH0005325M1 used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (36.74 kDa).
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1E2, monoclonal |
| conjugate | unconjugated |
| GenBank accession no. | NM_002656   |
| isotype | IgMκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | Q9UM63 |
| Biochem/physiol Actions: | The maternally-imprinted gene, PLAGL1 (pleiomorphic adenoma-like protein 1), functions as an oncogene as well as a tumor suppressor depending on the cell context. It has been found to exhibit anti-proliferative properties and regulate apoptosis and cell-cycle arrest via p53. |
| General description: | This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Many transcript variants encoding two different isoforms have been found for this gene. (provided by RefSeq) |
| Immunogen: | PLAGL1 (NP_002647.2, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence QPMQPLPESLASLHPSVSPGSPPPP |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |