Monoclonal Anti-POU3F2 antibody produced in mouse
SIGMA/WH0005454M1 - clone 6F6, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-39728; Anti-BRN2; Anti-OTF7; Anti-POU domain, class 3, transcription factor 2; Anti-POUF3
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 6F6, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_005604 |
isotype | IgG2bκ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1-5 μg/mL | |
UniProt accession no. | P20265 |
General description: | POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM |
Immunogen: | POU3F2 (NP_005595, 1 a.a. ~ 67 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MATAASNHYSLLTSSASIVHAEPPG |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |