Monoclonal Anti-PSMB4 antibody produced in mouse
SIGMA/WH0005692M1 - clone 6G7-E8, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-HN3; Anti-HsN3; Anti-PROS26; Anti-proteasome (prosome, macropain) subunit, beta type, 4
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 6G7-E8, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | BC000331 |
isotype | IgG1κ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
indirect ELISA: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | P28070 |
Biochem/physiol Actions: | Proteasome subunit β 4 (PSMB4) associates with senescence evasion factor (SNEV), various signaling factors, viral proteins and lipopolysaccharides. It modulates the assembly of the proteasome and may be involved in proteasome signal regulation. PSMB4 has a role in the progression of epithelial ovarian cancer and many other types of cancers. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | Proteasome subunit β 4 (PSMB4), also referred to as 20S proteasome subunit β-7, is a non-catalytic β subunit of the 20S proteasome. It is composed of 233 amino acids and the gene encoding it is localized on human chromosome 1q21.3. |
Immunogen: | PSMB4 (AAH00331, 1 a.a. ~ 264 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MEAFLGSRSGLWAGGPAPGQFYRIP |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |