Monoclonal Anti-RP2 antibody produced in mouse
SIGMA/WH0006102M2 - clone 5C10, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-KIAA0215; Anti-retinitis pigmentosa 2 (X-linked recessive)
Product Type: Chemical
Western Blotting RP2 monoclonal antibody, clone 5C10 Western Blot analysis of RP2 expression in HeLa S3 NE.
Western Blotting Western Blot analysis of RP2 expression in transfected 293T cell line by RP2 monoclonal antibody, clone 5C10. Lanes Lane 1: RP2 transfected lysate (39.6 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (36.74 kDa).
ELISA Detection limit for recombinant GST tagged RP2 is approximately 0.03 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 5C10, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | NM_006915   |
| isotype | IgG2bκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O75695 |
| General description: | The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death (provided by RefSeq) |
| Immunogen: | RP2 (NP_008846, 251 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence RKLIDEMVGKGFFLVQTKEVSMKAE |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |