Monoclonal Anti-TCF4 antibody produced in mouse
SIGMA/WH0006925M2 - clone 1F6, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-E22; Anti-ITF2; Anti-SEF2; Anti-SEF21; Anti-SEF21A; Anti-SEF21B; Anti-transcription factor 4
MDL Number: MFCD02097475
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 1F6, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | BC031056.1 |
isotype | IgG1κ |
Quality Level | 100 |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | indirect ELISA: suitable |
western blot: 1-5 μg/mL | |
UniProt accession no. | P15884 |
Biochem/physiol Actions: | Transcription factor 4 (TCF4) acts a regulator of cellular growth and differentiation. It has a role in the development of central nervous system. Defects in TCF4 gene are associated with Pitt-Hopkins syndrome. The protein has also been linked to susceptibility to schizophrenia. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | Transcription factor 4 (TCF4), also known as E2-2, is a helix-loop-helix transcription factor. It is part of the E protein family and is expressed in the cornea during development. The gene encoding TCF4 is localized on human chromosome 18q21. |
Immunogen: | TCF4 (AAH31056.1, 1 a.a. ~ 365 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MHHQQRMAALGTDKELSDLLDFSAM |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |