Monoclonal Anti-ZNF38 antibody produced in mouse
SIGMA/WH0007589M9 - clone 4B3, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-DKFZp434L134; Anti-DKFZp686H10254; Anti-NYREN21; Anti-ZSCAN21; Anti-Zipro1; Anti-zinc finger protein 38
Product Type: Chemical
Western Blotting Western Blot analysis of ZSCAN21 expression in transfected 293T cell line by ZNF38 monoclonal antibody, clone 4B3. Lanes Lane 1: ZSCAN21 transfected lysate (50.9 kDa). Lane 2: Non-transfected lysate.
Western Blotting ZSCAN21 monoclonal antibody, clone 4B3. Western Blot analysis of ZSCAN21 expression in human kidney.
Western Blotting ZSCAN21 monoclonal antibody, clone 4B3. Western Blot analysis of ZSCAN21 expression in H9c2(2-1).
Western Blotting QC Western Blot detection against Immunogen (77.55 kDa).
ELISA Detection limit for recombinant GST tagged ZSCAN21 is 1 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4B3, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | BC047309   |
| isotype | IgG2aκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9Y5A6 |
| Biochem/physiol Actions: | The gene ZSCAN21 (zinc finger and SCAN domain containing 21) encodes a transcription factor that transcriptionally regulates the gene SNCA that encodes α-synuclein in primary neuronal cultures. α-Synuclein is a presynaptic neuronal protein that is associated with Parkinson disease (PD). Therefore, the ZSCAN21 gene may serve as a potential target in the treatment of PD. |
| General description: | The gene ZSCAN21 (zinc finger and SCAN domain containing 21), also referred to as NY-REN-21, encodes a C2H2 type multi-finger protein that contains an N-terminal SCAN (SRE-ZBP, CTfin51, AW-1 (ZNF174), and Number 18 cDNA or ZnF20) domain and a predicted coil at the central region. The SCAN domain has the ability to form homodimers. |
| Immunogen: | ZSCAN21 (AAH47309.1, 1 a.a. ~ 473 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MMTKVLGMAPVLGPRPPQEQVGPLM |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |