Monoclonal Anti-PAX8 antibody produced in mouse
SIGMA/WH0007849M3 - clone 3B11, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-paired box gene 8
Product Type: Chemical
Western Blotting PAX8 monoclonal antibody, clone 3B11. Western Blot analysis of PAX8 expression in RIN-m5F. (60kD,Endocrinology Vol. 140, No. 10 4651-4658,http://endo.endojournals.org/cgi/content/full/140/10/4651)
Western Blotting QC Western Blot detection against Immunogen (34.32 kDa).
ELISA Detection limit for recombinant GST tagged PAX8 is approximately 3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3B11, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_003466   |
| isotype | IgG2bκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q06710 |
| General description: | This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. (provided by RefSeq) |
| Immunogen: | PAX8 (NP_003457, 300 a.a. ~ 377 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence DPHSPFAIKQETPEVSSSSSTPSSL |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |