Monoclonal Anti-CSRP3 antibody produced in mouse
SIGMA/WH0008048M3 - clone 6D2, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CLP; Anti-CMD1M; Anti-CRP3; Anti-LMO4; Anti-MGC14488; Anti-MGC61993; Anti-MLP; Anti-cysteine and glycine-rich protein 3 (cardiac LIM protein)
MDL Number: MFCD03096993
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to CSRP3 on HeLa cell. [antibody concentration 10 μg/mL]
Enhanced Validation-RNAi Western blot analysis of CSRP3 over-expressed 293 cell line, cotransfected with CSRP3 Validated Chimera RNAi. Blot probed with CSRP3 monoclonal antibody, clone 6D2. GAPDH (36.1 kDa) used as specificity and loading control.
Western Blotting Western Blot analysis of CSRP3 expression in transfected 293T cell line by CSRP3 monoclonal antibody, clone 6D2. Lanes Lane 1: CSRP3 transfected lysate (20.969 kDa). Lane 2: Non-transfected lysate.
Western Blotting CSRP3 monoclonal antibody, clone 6D2. Western Blot analysis of CSRP3 expression in HeLa S3 NE.
Western Blotting QC Western Blot detection against Immunogen (36.74 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 6D2, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_003476   |
| isotype | IgG2aκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | immunofluorescence: suitable |
| indirect ELISA: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | P50461 |
| General description: | This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5′ UTR, but encoding the same protein, have been found for this gene. (provided by RefSeq) |
| Immunogen: | CSRP3 (NP_003467, 95 a.a. ~ 194 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence SPKPARSVTTSNPSKFTAKFGESEK |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |