Monoclonal Anti-TNFSF12 antibody produced in mouse
SIGMA/WH0008742M1 - clone 4H3, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-APO3L; Anti-DR3LG; Anti-MGC20669; Anti-TWEAK; Anti-tumor necrosis factor (ligand) superfamily, member 12
MDL Number: MFCD02095846
Product Type: Chemical
Western Blotting TNFSF12 monoclonal antibody, clone 4H3. Western Blot analysis of TNFSF12 expression in Raw 264.7.
Western Blotting QC Western Blot detection against Immunogen (35.2 kDa).
ELISA Detection limit for recombinant GST tagged TNFSF12 is approximately 0.03 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4H3, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | BC019047   |
| isotype | IgG2aκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O43508 |
| General description: | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. (provided by RefSeq) |
| Immunogen: | TNFSF12 (AAH19047, 49 a.a. ~ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence SLSAQEPAQEELVAEEDQDPSELNP |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |