Monoclonal Anti-AKAP4 antibody produced in mouse
SIGMA/WH0008852M2 - clone 4C10, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-A kinase (PRKA) anchor protein 4; Anti-AKAP82; Anti-FSC1; Anti-HI; Anti-hAKAP82; Anti-p82
MDL Number: MFCD03454715
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 4C10, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_003886 ![]() ![]() |
isotype | IgG2aκ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | capture ELISA: suitable |
ELISA: suitable | |
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | Q5JQC9 ![]() ![]() |
Biochem/physiol Actions: | A-kinase anchoring protein 4 (AKAP4) functions in regulating the development and motility of sperms. This protein is considered a cancer-testis antigen (CTA) and is involved in eliciting an immune response in prostate cancer and multiple myeloma models. Higher levels of AKAP4 are seen in ovarian carcinoma. AKAP4 acts as a biomarker in the detection of early stages of lung cancer. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | A-kinase anchoring protein 4 (AKAP4) is a member of the AKAP family and is found abundantly in the sperm flagellum. The AKAP4 gene is mapped on the human chromosome at Xp11.22. |
Immunogen: | AKAP4 (NP_003877, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MMAYSDTTMMSDDIDWLRSHRGVCK |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |