Monoclonal Anti-MTA1 antibody produced in mouse
SIGMA/WH0009112M2 - clone 4D11, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-metastasis associated 1
MDL Number: MFCD07370404
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to MTA1 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting MTA1 monoclonal antibody, clone 4D11. Western Blot analysis of MTA1 expression in NIH/3T3.
Western Blotting MTA1 monoclonal antibody, clone 4D11. Western Blot analysis of MTA1 expression in PC-12.
Western Blotting MTA1 monoclonal antibody, clone 4D11 Western Blot analysis of MTA1 expression in HeLa S3 NE.
ELISA Detection limit for recombinant GST tagged MTA1 is approximately 3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4D11, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_004689   |
| isotype | IgG3κ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q8K4B0 |
| General description: | This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. (provided by RefSeq) |
| Immunogen: | MTA1 (NP_004680, 601 a.a. ~ 700 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MPSRGLANHGQTRHMGPSRNLLLNG |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |