Monoclonal Anti-SLK antibody produced in mouse
SIGMA/WH0009748M1 - clone 3E9, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-KIAA0204; Anti-STE20-like kinase (yeast); Anti-STK2; Anti-bA16H23.1; Anti-se209
Product Type: Chemical
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | 3E9, monoclonal |
conjugate | unconjugated |
form | buffered aqueous solution |
GenBank® accession no. | NM_014720 ![]() ![]() |
isotype | IgG1κ |
Quality Level | 100 ![]() |
shipped in | dry ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
indirect ELISA: suitable | |
western blot: 1-5 μg/mL | |
UniProt accession no. | Q9H2G2 ![]() ![]() |
Biochem/physiol Actions: | STE20 like kinase (SLK) is a modulator of cell motility. It phosphorylates cytoskeleton-bound proteins, which take part in the remodeling of migratory cell architecture. SLK is also involved in mitogen-activated protein kinase pathways. It acts as an activator of Jun N-terminal kinase (JNK) and transactivates tumor suppressor p53. |
General description: | STE20 like kinase (SLK) is a 1204 amino acid serine/threonine kinase. It possesses a kinase domain located at the amino-terminal and a C-terminal regulatory domain with coiled-coils. SLK is group V germinal center kinase that is expressed in the nucleus, cytosol, microtubules and centrosomes. The SLK gene is localized on human chromosome 10q24.33. |
Immunogen: | SLK (NP_055535, 1126 a.a. ~ 1235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence KHENQMRDLQLQCEANVRELHQLQN |
Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
Physical form: | Solution in phosphate buffered saline, pH 7.4 |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |