Monoclonal Anti-DNM1L antibody produced in mouse
SIGMA/WH0010059M1 - clone 3B5, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-DLP1; Anti-DRP1; Anti-DVLP; Anti-DYMPLE; Anti-HDYNIV; Anti-VPS1; Anti-dynamin 1-like
MDL Number: MFCD02262789
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of monoclonal antibody to DNM1L on formalin-fixed paraffin-embedded human leiomyosarcoma tissue. [antibody concentration 1 μg/mL]
Western Blotting DNM1L monoclonal antibody, clone 3B5 Western Blot analysis of DNM1L expression in K-562.
Western Blotting Western Blot analysis of DNM1L expression in transfected 293T cell line by DNM1L monoclonal antibody, clone 3B5. Lanes Lane 1: DNM1L transfected lysate (79 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (103.84 kDa).
ELISA Detection limit for recombinant GST tagged DNM1L is approximately 0.3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3B5, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | BC024590   |
| isotype | IgG2bκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| indirect ELISA: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O00429 |
| Application: | Monoclonal Anti-DNM1L antibody produced in mouse has been used in Western blotting. |
| Biochem/physiol Actions: | Dynamin 1 like (DNM1L) has a role in peroxisomal and mitochondrial division. It may promote cardiovascular calcification. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Dynamin 1 like (DNM1L) is a dynamin guanosine triphosphatase and a part of the dynamin superfamily of GTPases. The gene encoding DNM1L is localized on human chromosome 12p11.21. DNM1L mRNA is expressed in the kidneys. The protein is localized to the cytoplasm and when activated, translocates to membranes of organelles. |
| Immunogen: | DNM1L (AAH24590.1, 1 a.a. ~ 710 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MEALIPVINKLQDVFNTVGADIIQL |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |