Monoclonal Anti-EDAR antibody produced in mouse
SIGMA/WH0010913M1 - clone 6C12, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-DL; Anti-ED1R; Anti-ED3; Anti-ED5; Anti-EDA1R; Anti-EDA3; Anti-EDAA1R; Anti-ectodysplasin A receptor
Product Type: Chemical
Western Blotting EDAR monoclonal antibody, clone 6C12. Western Blot analysis of EDAR expression in human kidney.
Western Blotting QC Western Blot detection against Immunogen (38.39 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 6C12, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | NM_022336   |
| isotype | IgG2bκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q9UNE0 |
| General description: | This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. (provided by RefSeq) |
| Immunogen: | EDAR (NP_071731, 64 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence TKDEDYGCVPCPAEKFSKGGYQICR |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |