Monoclonal Anti-LILRA3 antibody produced in mouse
SIGMA/WH0011026M1 - clone 2E9, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CD85E; Anti-HM31; Anti-HM43; Anti-ILT6; Anti-LIR4; Anti-e3; Anti-leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
Product Type: Chemical
Western Blotting Western Blot analysis of LILRA3 expression in transfected 293T cell line by LILRA3 monoclonal antibody, clone 2E9. Lanes Lane 1: LILRA3 transfected lysate (50.485 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (74.03 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 2E9, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank accession no. | BC028208   |
| isotype | IgG1κ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q8N6C8 |
| General description: | Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM |
| Immunogen: | LILRA3 (AAH28208.1, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MTSILTVLICLGLSLDPRTHVQAGP |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |