Monoclonal Anti-LDB3 antibody produced in mouse
SIGMA/WH0011155M6 - clone 3C8, ascites fluid
Synonym: Anti-CYPHER; Anti-KIAA01613; Anti-KIAA0613; Anti-LIM domain binding 3; Anti-ORACLE; Anti-PDLIM6; Anti-ZASP
Product Type: Chemical
Western Blotting Western Blot analysis of LDB3 expression in transfected 293T cell line by LDB3 monoclonal antibody, clone 3C8. Lanes Lane 1: LDB3 transfected lysate (31 kDa). Lane 2: Non-transfected lysate.
Western Blotting LDB3 monoclonal antibody, clone 3C8 Western Blot analysis of LDB3 expression in A-431.
Western Blotting QC Western Blot detection against Immunogen (56.87 kDa).
ELISA Detection limit for recombinant GST tagged LDB3 is approximately 0.03 ng/mL as a capture antibody.
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 3C8, monoclonal |
| conjugate | unconjugated |
| GenBank® accession no. | BC010929   |
| isotype | IgG2bκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O75112 |
| General description: | This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. (provided by RefSeq) |
| Immunogen: | LDB3 (AAH10929, 1 a.a. ~ 283 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MSYSVTLTGPGPWGFRLQGGKDFNM |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |