Monoclonal Anti-CBX3 antibody produced in mouse
SIGMA/WH0011335M1 - clone 1G12-1D9, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-HECH; Anti-HP1GAMMA; Anti-HP1Hsgamma; Anti-chromobox homolog 3 (HP1 gamma homolog, Drosophila)
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to CBX3 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting CBX3 monoclonal antibody, clone 1G12-1D9 Western Blot analysis of CBX3 expression in HeLa.
Western Blotting QC Western Blot detection against Immunogen (45.87 kDa).
ELISA Detection limit for recombinant GST tagged CBX3 is approximately 0.03 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1G12-1D9, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| GenBank® accession no. | BC000954   |
| isotype | IgG2aκ |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| technique(s) | indirect ELISA: suitable |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q13185 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5′ UTR, have been found for this gene. (provided by RefSeq) |
| Immunogen: | CBX3 (AAH00954, 1 a.a. ~ 183 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MASNKTTLQKMGKKQNGKSKKVEEA |
| Legal Information: | GenBank is a registered trademark of United States Department of Health and Human Services |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |